4N5Z
Crystal structure of aerosol transmissible influenza H5 hemagglutinin mutant (N158D, N224K, Q226L and T318I) from the influenza virus A/Viet Nam/1203/2004 (H5N1)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, C, E, G, I...) | Hemagglutinin HA1 chain | polymer | 334 | 37961.2 | 15 | UniProt (Q6DQ33) Pfam (PF00509) UniProt (by SIFTS) (Q5EP31) | Influenza A virus | |
| 2 | AA, BA, CA, DA, P... (B, D, F, H, J...) | Hemagglutinin | polymer | 181 | 20881.1 | 15 | UniProt (Q6DQ33) Pfam (PF00509) | Influenza A virus | |
| 3 | EA, GA, HA, JA, LA... (e, g, h, j, l...) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 12 | In PDB GlyTouCan (G15407YE) | |||
| 4 | AB, FA, IA, KA, MA... (0, f, i, k, m...) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 11 | In PDB GlyTouCan (G42666HT) | |||
| 5 | BB, CB, DB, EB, FB... (C, K, M, O, Y...) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 7 | Chemie (NAG) |
Sequence modifications
A, C, E, G, I, K, M, O, Q, S, U, W, Y, a, c: 11 - 333 (UniProt: Q6DQ33)
B, D, F, H, J, L, N, P, R, T, V, X, Z, b, d: 1 - 174 (UniProt: Q6DQ33)
| PDB | External Database | Details |
|---|---|---|
| Ala 7 | - | expression tag |
| Asp 8 | - | expression tag |
| Pro 9 | - | expression tag |
| Gly 10 | - | expression tag |
| Asp 158 | Asn 170 | engineered mutation |
| Lys 224 | Asn 236 | engineered mutation |
| Leu 226 | Gln 238 | engineered mutation |
| Ile 318 | Thr 331 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Ser 175 | - | expression tag |
| Gly 176 | - | expression tag |
| Arg 177 | - | expression tag |
| Leu 178 | - | expression tag |
| Val 179 | - | expression tag |
| Pro 180 | - | expression tag |
| Arg 181 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 30 |
| Total formula weight | 882634.1 | |
| Branched | Number of molecules | 23 |
| Total formula weight | 11706.9 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1548.5 | |
| All* | Total formula weight | 895889.5 |
