4N5M

Crystal structure of (R)-3-hydroxybutyryl-CoA dehydrogenase from Ralstonia eutropha in complexed with acetoacetyl-CoA

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Acetoacetyl-CoA reductase	polymer	270	29399.2	2	UniProt (P14697) Pfam (PF00106)	Ralstonia eutropha	(R)-3-hydroxybutyrylCoA dehydrogenase
2	C, G (A, B)	ACETOACETYL-COENZYME A	non-polymer		851.6	2	Chemie (CAA)
3	D, E, F, H, I... (A, B)	GLYCEROL	non-polymer		92.1	6	Chemie (GOL)
4	K, L (A, B)	water	water		18.0	543	Chemie (HOH)

Sequence modifications

A, B: 1 - 246 (UniProt: P14697)

PDB	External Database	Details
Met -23	-	expression tag
Ser -22	-	expression tag
Tyr -21	-	expression tag
Tyr -20	-	expression tag
His -19	-	expression tag
His -18	-	expression tag
His -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
Asp -13	-	expression tag
Tyr -12	-	expression tag
Asp -11	-	expression tag
Ile -10	-	expression tag
Pro -9	-	expression tag
Thr -8	-	expression tag
Glu -7	-	expression tag
Asn -6	-	expression tag
Leu -5	-	expression tag
Tyr -4	-	expression tag
Phe -3	-	expression tag
Gln -2	-	expression tag
Gly -1	-	expression tag
Ala 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	58798.3
Non-Polymers*	Number of molecules	8
	Total formula weight	2255.8
All*	Total formula weight	61054.1

*Water molecules are not included.