4N3Y

Crystal structure of Rabex-5CC and Rabaptin-5C21 complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Rab5 GDP/GTP exchange factor	polymer	45	5261.9	1	UniProt (Q9UJ41)	Homo sapiens (human)	RAP1, Rabaptin-5-associated exchange factor for Rab5, Rabex-5
2	B, C (B, C)	Rab GTPase-binding effector protein 1	polymer	92	10701.1	2	UniProt (Q15276)	Homo sapiens (human)	Rabaptin-4, Rabaptin-5, Rabaptin-5alpha, Renal carcinoma antigen NY-REN-17
3	D, E, F (A, B, C)	water	water		18.0	187	Chemie (HOH)

Sequence modifications

A: 413 - 455 (UniProt: Q9UJ41)

PDB	External Database	Details
Gly 411	-	expression tag
Ser 412	-	expression tag

B, C: 552 - 642 (UniProt: Q15276)

PDB	External Database	Details
Met 551	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	26664.0
All*	Total formula weight	26664.0

*Water molecules are not included.