4N37
Structure of langerin CRD I313 D288 complexed with Me-Man
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | C-type lectin domain family 4 member K | polymer | 136 | 15562.3 | 4 | UniProt (Q9UJ71) Pfam (PF00059) | Homo sapiens (human) | Langerin |
| 2 | E, G, I, K (A, B, C, D) | methyl alpha-D-mannopyranoside | non-polymer | 194.2 | 4 | Chemie (MMA) | |||
| 3 | F, H, J, L (A, B, C, D) | CALCIUM ION | non-polymer | 40.1 | 4 | Chemie (CA) | |||
| 4 | M, N, O, P (A, B, C, D) | water | water | 18.0 | 474 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 193 - 328 (UniProt: Q9UJ71)
| PDB | External Database | Details |
|---|---|---|
| Ala 278 | Val 278 | variant |
| Asp 288 | Asn 288 | engineered mutation |
| Ile 313 | Lys 313 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 62249.4 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 937.0 | |
| All* | Total formula weight | 63186.4 |
