4N36
Structure of langerin CRD I313 D288 complexed with Me-GlcNAc
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | C-type lectin domain family 4 member K | polymer | 136 | 15562.3 | 4 | UniProt (Q9UJ71) Pfam (PF00059) | Homo sapiens (human) | Langerin |
| 2 | E, G, I, K (A, B, C, D) | methyl 2-acetamido-2-deoxy-alpha-D-glucopyranoside | non-polymer | 235.2 | 4 | Chemie (2F8) | |||
| 3 | F, H, J, L (A, B, C, D) | CALCIUM ION | non-polymer | 40.1 | 4 | Chemie (CA) | |||
| 4 | M (D) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 5 | N, O, P, Q (A, B, C, D) | water | water | 18.0 | 544 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 193 - 328 (UniProt: Q9UJ71)
| PDB | External Database | Details |
|---|---|---|
| Ala 278 | Val 278 | variant |
| Asp 288 | Asn 288 | engineered mutation |
| Ile 313 | Lys 313 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 62249.4 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 1125.6 | |
| All* | Total formula weight | 63374.9 |
