4MZW

CRYSTAL STRUCTURE OF NU-CLASS GLUTATHIONE TRANSFERASE YGHU FROM Streptococcus sanguinis SK36, COMPLEX WITH GLUTATHIONE DISULFIDE, TARGET EFI-507286

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Glutathione S-Transferase	polymer	284	31711.9	2	UniProt (A3CNR0) Pfam (PF02798) Pfam (PF13410)	Streptococcus sanguinis
2	C, D (A, B)	OXIDIZED GLUTATHIONE DISULFIDE	non-polymer		612.6	2	Chemie (GDS)
3	E (B)	ACETATE ION	non-polymer		59.0	1	Chemie (ACT)
4	F, G (A, B)	water	water		18.0	472	Chemie (HOH)

Sequence modifications

A, B: 1 - 262 (UniProt: A3CNR0)

PDB	External Database	Details
Met -22	-	expression tag
His -21	-	expression tag
His -20	-	expression tag
His -19	-	expression tag
His -18	-	expression tag
His -17	-	expression tag
His -16	-	expression tag
Ser -15	-	expression tag
Ser -14	-	expression tag
Gly -13	-	expression tag
Val -12	-	expression tag
Asp -11	-	expression tag
Leu -10	-	expression tag
Gly -9	-	expression tag
Thr -8	-	expression tag
Glu -7	-	expression tag
Asn -6	-	expression tag
Leu -4	-	expression tag
Tyr -3	-	expression tag
Phe -2	-	expression tag
Gln -1	-	expression tag
Ser 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	63423.9
Non-Polymers*	Number of molecules	3
	Total formula weight	1284.3
All*	Total formula weight	64708.2

*Water molecules are not included.