4MYW
Structure of HSV-2 gD bound to nectin-1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Envelope glycoprotein D | polymer | 294 | 32994.5 | 2 | UniProt (P03172) Pfam (PF01537) | Human herpesvirus 2 (HHV-2) | gD |
| 2 | B, D (B, D) | Poliovirus receptor-related protein 1 | polymer | 331 | 36938.5 | 2 | UniProt (Q15223) Pfam (PF07686) Pfam (PF08205) Pfam (PF13927) | Homo sapiens (human) | Herpes virus entry mediator C, Herpesvirus entry mediator C, HveC, Herpesvirus Ig-like receptor, HIgR, Nectin-1 |
| 3 | E, F (E, F) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | In PDB GlyTouCan (G42666HT) | |||
| 4 | G, H (A, C) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
| 5 | I, J, K, L (A, B, C, D) | water | water | 18.0 | 57 | Chemie (HOH) |
Sequence modifications
A, C: 1 - 285 (UniProt: P03172)
B, D: 30 - 335 (UniProt: Q15223)
| PDB | External Database | Details |
|---|---|---|
| Ala -2 | - | expression tag |
| Asp -1 | - | expression tag |
| Leu 0 | - | expression tag |
| Gln 27 | Arg 52 | SEE REMARK 999 |
| His 286 | - | expression tag |
| His 287 | - | expression tag |
| His 288 | - | expression tag |
| His 289 | - | expression tag |
| His 290 | - | expression tag |
| His 291 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Met 16 | - | expression tag |
| Ala 17 | - | expression tag |
| Ser 18 | - | expression tag |
| Met 19 | - | expression tag |
| Thr 20 | - | expression tag |
| Gly 21 | - | expression tag |
| Gly 22 | - | expression tag |
| Gln 23 | - | expression tag |
| Gln 24 | - | expression tag |
| Met 25 | - | expression tag |
| Gly 26 | - | expression tag |
| Arg 27 | - | expression tag |
| Asp 28 | - | expression tag |
| Pro 29 | - | expression tag |
| Ala 336 | - | expression tag |
| Ala 337 | - | expression tag |
| Ala 338 | - | expression tag |
| Leu 339 | - | expression tag |
| Glu 340 | - | expression tag |
| His 341 | - | expression tag |
| His 342 | - | expression tag |
| His 343 | - | expression tag |
| His 344 | - | expression tag |
| His 345 | - | expression tag |
| His 346 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 139865.9 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 848.8 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 442.4 | |
| All* | Total formula weight | 141157.1 |
