4MWZ
Crystal structure of N-methyl transferase from Plasmodium vivax complexed with S-adenosyl methionine, phosphate and amodiaquine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Phosphoethanolamine N-methyltransferase, putative | polymer | 267 | 31206.9 | 2 | UniProt (A5K867) Pfam (PF13649) | Plasmodium vivax | |
| 2 | C, F (A, B) | S-ADENOSYLMETHIONINE | non-polymer | 398.4 | 2 | Chemie (SAM) | |||
| 3 | D, G (A, B) | PHOSPHATE ION | non-polymer | 95.0 | 2 | Chemie (PO4) | |||
| 4 | E, I (A, B) | BETA-MERCAPTOETHANOL | non-polymer | 78.1 | 2 | Chemie (BME) | |||
| 5 | H (B) | 4-[(7-CHLOROQUINOLIN-4-YL)AMINO]-2-[(DIETHYLAMINO)METHYL]PHENOL | non-polymer | 355.9 | 1 | Chemie (CQA) | |||
| 6 | J, K (A, B) | water | water | 18.0 | 727 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 264 (UniProt: A5K867)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 62413.8 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1498.9 | |
| All* | Total formula weight | 63912.8 |
