4MWZ
Crystal structure of N-methyl transferase from Plasmodium vivax complexed with S-adenosyl methionine, phosphate and amodiaquine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Phosphoethanolamine N-methyltransferase, putative | polymer | 267 | 31206.9 | 2 | UniProt (A5K867) Pfam (PF13649) | Plasmodium vivax | |
| 2 | C, F (A, B) | S-ADENOSYLMETHIONINE | non-polymer | 398.4 | 2 | Chemie (SAM) PubChem (5136) PubChem (34755) PubChem (58633578) PubChem (60038769) PubChem (73897310) PubChem (58766358) PubChem (87224684) PubChem (131697735) PubChem (9865603) PubChem (145712080) PubChem (12312798) PubChem (132988922) PubChem (134692588) PubChem (135030730) PubChem (140459785) PubChem (163046094) | |||
| 3 | D, G (A, B) | PHOSPHATE ION | non-polymer | 95.0 | 2 | Chemie (PO4) PubChem (1061) | |||
| 4 | E, I (A, B) | BETA-MERCAPTOETHANOL | non-polymer | 78.1 | 2 | Chemie (BME) | |||
| 5 | H (B) | 4-[(7-CHLOROQUINOLIN-4-YL)AMINO]-2-[(DIETHYLAMINO)METHYL]PHENOL | non-polymer | 355.9 | 1 | Chemie (CQA) PubChem (2165) | |||
| 6 | J, K (A, B) | water | water | 18.0 | 727 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 264 (UniProt: A5K867)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 62413.8 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1498.9 | |
| All* | Total formula weight | 63912.8 |
