4MWZ

Crystal structure of N-methyl transferase from Plasmodium vivax complexed with S-adenosyl methionine, phosphate and amodiaquine

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Phosphoethanolamine N-methyltransferase, putative	polymer	267	31206.9	2	UniProt (A5K867) Pfam (PF13649) In PDB	Plasmodium vivax
2	A, B	S-ADENOSYLMETHIONINE	non-polymer		398.4	2	Chemie (SAM)
3	A, B	PHOSPHATE ION	non-polymer		95.0	2	Chemie (PO4)
4	A, B	BETA-MERCAPTOETHANOL	non-polymer		78.1	2	Chemie (BME)
5	B	4-[(7-CHLOROQUINOLIN-4-YL)AMINO]-2-[(DIETHYLAMINO)METHYL]PHENOL	non-polymer		355.9	1	Chemie (CQA)
6		water	water		18.0	727	Chemie (HOH)

Sequence modifications

A, B: 1 - 264 (UniProt: A5K867)

PDB	External Database	Details
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	62413.8
Non-Polymers*	Number of molecules	7
	Total formula weight	1498.9
All*	Total formula weight	63912.8

*Water molecules are not included.