4MV3

Crystal Structure of Biotin Carboxylase from Haemophilus influenzae in Complex with AMPPCP and Bicarbonate

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Biotin carboxylase	polymer	468	51346.6	1	UniProt (P43873) Pfam (PF00289) Pfam (PF02786) Pfam (PF02785) In PDB	Haemophilus influenzae	Acetyl-CoA carboxylase subunit A, ACC
2	A	PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER	non-polymer		505.2	1	Chemie (ACP)
3	A	1,2-ETHANEDIOL	non-polymer		62.1	1	Chemie (EDO)
4	A	BICARBONATE ION	non-polymer		61.0	1	Chemie (BCT)
5		water	water		18.0	258	Chemie (HOH)

Sequence modifications

A: 1 - 448 (UniProt: P43873)

PDB	External Database	Details
Met -19	-	expression tag
Gly -18	-	expression tag
Ser -17	-	expression tag
Ser -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	51346.6
Non-Polymers*	Number of molecules	3
	Total formula weight	628.3
All*	Total formula weight	51974.8

*Water molecules are not included.