4MTI
Crystal structure of cIAP1 BIR3 bound to T3258042
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Baculoviral IAP repeat-containing protein 2 | polymer | 115 | 13294.8 | 2 | UniProt (Q13490) Pfam (PF00653) In PDB | Homo sapiens (human) | C-IAP1, IAP homolog B, Inhibitor of apoptosis protein 2, IAP-2, hIAP-2, hIAP2, RING finger protein 48, TNFR2-TRAF-signaling complex protein 2 |
2 | A, B | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
3 | A, B | (3S,8aR)-2-[(2S)-2-cyclohexyl-2-{[(2S)-2-(methylamino)butanoyl]amino}acetyl]-N-[(4R)-3,4-dihydro-2H-chromen-4-yl]octahydropyrrolo[1,2-a]pyrazine-3-carboxamide | non-polymer | 539.7 | 2 | Chemie (2DX) | |||
4 | water | water | 18.0 | 124 | Chemie (HOH) |
Sequence modifications
A, B: 254 - 346 (UniProt: Q13490)
PDB | External Database | Details |
---|---|---|
Met 232 | - | expression tag |
Gly 233 | - | expression tag |
Ser 234 | - | expression tag |
Ser 235 | - | expression tag |
His 236 | - | expression tag |
His 237 | - | expression tag |
His 238 | - | expression tag |
His 239 | - | expression tag |
His 240 | - | expression tag |
His 241 | - | expression tag |
Ser 242 | - | expression tag |
Ser 243 | - | expression tag |
Gly 244 | - | expression tag |
Glu 245 | - | expression tag |
Asn 246 | - | expression tag |
Leu 247 | - | expression tag |
Tyr 248 | - | expression tag |
Phe 249 | - | expression tag |
Gln 250 | - | expression tag |
Gly 251 | - | expression tag |
Gly 252 | - | expression tag |
Ser 253 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 26589.7 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 1210.2 | |
All* | Total formula weight | 27799.9 |