4MSP
Crystal structure of human peptidyl-prolyl cis-trans isomerase FKBP22 (aka FKBP14) containing two EF-hand motifs
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Peptidyl-prolyl cis-trans isomerase FKBP14 | polymer | 200 | 22883.0 | 2 | UniProt (Q9NWM8) Pfam (PF00254) | Homo sapiens (human) | PPIase FKBP14, 22 kDa FK506-binding protein, 22 kDa FKBP, FKBP-22, FK506-binding protein 14, FKBP-14, Rotamase |
| 2 | C, D, E, K, L (A, B) | CALCIUM ION | non-polymer | 40.1 | 5 | Chemie (CA) | |||
| 3 | F, G (A) | PENTAETHYLENE GLYCOL | non-polymer | 238.3 | 2 | Chemie (1PE) | |||
| 4 | H, I, J, M, N... (A, B) | S-1,2-PROPANEDIOL | non-polymer | 76.1 | 8 | Chemie (PGO) | |||
| 5 | R, S (A, B) | water | water | 18.0 | 280 | Chemie (HOH) |
Sequence modifications
A, B: 2 - 192 (UniProt: Q9NWM8)
| PDB | External Database | Details |
|---|---|---|
| Ala -7 | - | expression tag |
| Met -6 | - | expression tag |
| Ala -5 | - | expression tag |
| Asp -4 | - | expression tag |
| Ile -3 | - | expression tag |
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| Glu 0 | - | expression tag |
| Phe 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 45766.0 | |
| Non-Polymers* | Number of molecules | 15 |
| Total formula weight | 1285.7 | |
| All* | Total formula weight | 47051.7 |
