4MPG
Crystal structure of human glutathione transferase theta-2, complex with glutathione and unknown ligand, target EFI-507257
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Glutathione S-transferase theta-2 | polymer | 266 | 30112.8 | 2 | UniProt (P0CG29) Pfam (PF02798) Pfam (PF00043) UniProt (by SIFTS) (P0CG30) | Homo sapiens (human) | GST class-theta-2 |
| 2 | C, D (A, B) | GLUTATHIONE | non-polymer | 307.3 | 2 | Chemie (GSH) | |||
| 3 | E (B) | UNKNOWN LIGAND | non-polymer | 1 | Chemie (UNL) | ||||
| 4 | F (B) | FORMIC ACID | non-polymer | 46.0 | 1 | Chemie (FMT) | |||
| 5 | G, H (A, B) | water | water | 18.0 | 288 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 244 (UniProt: P0CG29)
| PDB | External Database | Details |
|---|---|---|
| Met -21 | - | expression tag |
| His -20 | - | expression tag |
| His -19 | - | expression tag |
| His -18 | - | expression tag |
| His -17 | - | expression tag |
| His -16 | - | expression tag |
| His -15 | - | expression tag |
| Ser -14 | - | expression tag |
| Ser -13 | - | expression tag |
| Gly -12 | - | expression tag |
| Val -11 | - | expression tag |
| Asp -10 | - | expression tag |
| Leu -9 | - | expression tag |
| Gly -8 | - | expression tag |
| Thr -7 | - | expression tag |
| Glu -6 | - | expression tag |
| Asn -5 | - | expression tag |
| Leu -4 | - | expression tag |
| Tyr -3 | - | expression tag |
| Phe -2 | - | expression tag |
| Gln -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 60225.5 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 660.7 | |
| All* | Total formula weight | 60886.2 |
