4MP2
Crystal structure of pyruvate dehydrogenase kinase isoform 2 in complex with inhibitor PA1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 2, mitochondrial | polymer | 400 | 45233.4 | 1 | UniProt (Q15119) Pfam (PF10436) Pfam (PF02518) | Homo sapiens (human) | Pyruvate dehydrogenase kinase isoform 2, PDH kinase 2, PDKII |
| 2 | B (A) | (5-bromo-2,4-dihydroxyphenyl)(1,3-dihydro-2H-isoindol-2-yl)methanone | non-polymer | 334.2 | 1 | Chemie (PV1) | |||
| 3 | C (A) | L(+)-TARTARIC ACID | non-polymer | 150.1 | 1 | Chemie (TLA) | |||
| 4 | D (A) | water | water | 18.0 | 212 | Chemie (HOH) |
Sequence modifications
A: 9 - 407 (UniProt: Q15119)
| PDB | External Database | Details |
|---|---|---|
| Ser 8 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 45233.4 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 484.3 | |
| All* | Total formula weight | 45717.7 |
