4MLE
Human Glucokinase in Complex with Novel Amino Thiazole Activator
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Glucokinase | polymer | 455 | 51009.0 | 1 | UniProt (P35557) Pfam (PF00349) Pfam (PF03727) | Homo sapiens (human) | Hexokinase type IV, HK IV, Hexokinase-4, HK4, Hexokinase-D |
| 2 | B (A) | alpha-D-glucopyranose | non-polymer | 180.2 | 1 | Chemie (GLC) | |||
| 3 | C (A) | 3-(benzyloxy)-N-(4-methyl-1,3-thiazol-2-yl)pyridin-2-amine | non-polymer | 297.4 | 1 | Chemie (VO1) |
Sequence modifications
A: 12 - 465 (UniProt: P35557)
| PDB | External Database | Details |
|---|---|---|
| Met 11 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 51009.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 477.5 | |
| All* | Total formula weight | 51486.5 |
