4MKB
Hepatitis C Virus polymerase NS5B genotype 1b (BK) in complex with inhibitor 14 (N-(4-{(E)-2-[3-tert-butyl-2-methoxy-5-(3-oxo-2,3-dihydropyridazin-4-yl)phenyl]ethenyl}phenyl)methanesulfonamide)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | RNA-DIRECTED RNA POLYMERASE | polymer | 570 | 63354.7 | 2 | UniProt (P26663) Pfam (PF00998) In PDB | Hepatitis C virus (HCV) | |
| 2 | A, B | N-(4-{(E)-2-[3-tert-butyl-2-methoxy-5-(3-oxo-2,3-dihydropyridazin-4-yl)phenyl]ethenyl}phenyl)methanesulfonamide | non-polymer | 453.6 | 2 | Chemie (28V) | |||
| 3 | water | water | 18.0 | 904 | Chemie (HOH) |
Sequence modifications
A, B: 2 - 570 (UniProt: P26663)
| PDB | External Database | Details |
|---|---|---|
| His 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 126709.4 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 907.1 | |
| All* | Total formula weight | 127616.5 |
