4MK9
Hepatitis C Virus polymerase NS5B genotype 1b (BK) in complex with inhibitor 12 (N-{2-[3-tert-butyl-2-methoxy-5-(2-oxo-1,2-dihydropyridin-3-yl)phenyl]-1,3-benzoxazol-5-yl}methanesulfonamide)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | RNA-DIRECTED RNA POLYMERASE | polymer | 570 | 63354.7 | 2 | UniProt (P26663) Pfam (PF00998) In PDB | Hepatitis C virus (HCV) | NS5B, p68 |
2 | A, B | N-{2-[3-tert-butyl-2-methoxy-5-(2-oxo-1,2-dihydropyridin-3-yl)phenyl]-1,3-benzoxazol-5-yl}methanesulfonamide | non-polymer | 467.5 | 2 | Chemie (28R) | |||
3 | B | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
4 | water | water | 18.0 | 981 | Chemie (HOH) |
Sequence modifications
A, B: 2 - 570 (UniProt: P26663)
PDB | External Database | Details |
---|---|---|
His 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 126709.4 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 1027.2 | |
All* | Total formula weight | 127736.6 |