4MIT
Crystal structure of E. histolytica RacC bound to the EhPAK4 PBD
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Rho family GTPase | polymer | 186 | 20645.8 | 4 | UniProt (M7WE85) Pfam (PF00071) UniProt (by SIFTS) (Q24816) | Entamoeba histolytica | |
| 2 | E, F, G, H (E, F, G, H) | Serine/threonine protein kinase PAK, putative | polymer | 70 | 7505.1 | 4 | UniProt (N9UZ59) | Entamoeba histolytica | |
| 3 | I, M, Q, U (A, B, C, D) | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 4 | Chemie (GTP) PubChem (177679032) PubChem (135400627) PubChem (135487750) PubChem (136088935) PubChem (136803486) PubChem (135398633) PubChem (135544356) PubChem (135547949) PubChem (135600366) PubChem (135749822) PubChem (136005188) PubChem (136073923) PubChem (136240914) PubChem (136664747) PubChem (136772743) PubChem (136772744) PubChem (136803487) PubChem (137286749) PubChem (164715984) PubChem (171699466) | |||
| 4 | J, K, L, N, O... (A, B, C, D) | MAGNESIUM ION | non-polymer | 24.3 | 12 | Chemie (MG) PubChem (888) | |||
| 5 | AA, BA, CA, DA, EA... (C, D, E, F, G...) | water | water | 18.0 | 341 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 4 - 186 (UniProt: M7WE85)
E, F, G, H: 4 - 70 (UniProt: N9UZ59)
| PDB | External Database | Details |
|---|---|---|
| Ser 1 | - | expression tag |
| Asn 2 | - | expression tag |
| Ala 3 | - | expression tag |
| Leu 68 | Gln 65 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Ser 1 | - | expression tag |
| Asn 2 | - | expression tag |
| Ala 3 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 112603.6 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 2384.4 | |
| All* | Total formula weight | 114988.0 |
