4MIT

Crystal structure of E. histolytica RacC bound to the EhPAK4 PBD

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D	Rho family GTPase	polymer	186	20645.8	4	UniProt (M7WE85) Pfam (PF00071) UniProt (by SIFTS) (Q24816) In PDB	Entamoeba histolytica
2	E, F, G, H	Serine/threonine protein kinase PAK, putative	polymer	70	7505.1	4	UniProt (N9UZ59) Pfam (PF00786) In PDB	Entamoeba histolytica
3	A, B, C, D	GUANOSINE-5'-TRIPHOSPHATE	non-polymer		523.2	4	Chemie (GTP)
4	A, B, C, D	MAGNESIUM ION	non-polymer		24.3	12	Chemie (MG)
5		water	water		18.0	341	Chemie (HOH)

Sequence modifications

A, B, C, D: 4 - 186 (UniProt: M7WE85)

PDB	External Database	Details
Ser 1	-	expression tag
Asn 2	-	expression tag
Ala 3	-	expression tag
Leu 68	Gln 65	engineered mutation

E, F, G, H: 4 - 70 (UniProt: N9UZ59)

PDB	External Database	Details
Ser 1	-	expression tag
Asn 2	-	expression tag
Ala 3	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	112603.6
Non-Polymers*	Number of molecules	16
	Total formula weight	2384.4
All*	Total formula weight	114988.0

*Water molecules are not included.