4MIT
Crystal structure of E. histolytica RacC bound to the EhPAK4 PBD
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Rho family GTPase | polymer | 186 | 20645.8 | 4 | UniProt (M7WE85) Pfam (PF00071) UniProt (by SIFTS) (Q24816) | Entamoeba histolytica | |
| 2 | E, F, G, H (E, F, G, H) | Serine/threonine protein kinase PAK, putative | polymer | 70 | 7505.1 | 4 | UniProt (N9UZ59) Pfam (PF00786) | Entamoeba histolytica | |
| 3 | I, M, Q, U (A, B, C, D) | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 4 | Chemie (GTP) | |||
| 4 | J, K, L, N, O... (A, B, C, D) | MAGNESIUM ION | non-polymer | 24.3 | 12 | Chemie (MG) | |||
| 5 | AA, BA, CA, DA, EA... (C, D, E, F, G...) | water | water | 18.0 | 341 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 4 - 186 (UniProt: M7WE85)
E, F, G, H: 4 - 70 (UniProt: N9UZ59)
| PDB | External Database | Details |
|---|---|---|
| Ser 1 | - | expression tag |
| Asn 2 | - | expression tag |
| Ala 3 | - | expression tag |
| Leu 68 | Gln 65 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Ser 1 | - | expression tag |
| Asn 2 | - | expression tag |
| Ala 3 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 112603.6 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 2384.4 | |
| All* | Total formula weight | 114988.0 |
