4MHJ
Crystal structure of Fab H5M9 in complex with influenza virus hemagglutinin from A/goose/Guangdong/1/96 (H5N1)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E, F, H... (A, C, G, M, O...) | Hemagglutinin HA1 chain | polymer | 334 | 37812.7 | 6 | UniProt (Q9Q0U6) Pfam (PF00509) | Influenza A virus | |
| 2 | B, D, G, I, Q... (B, D, N, P, I...) | Hemagglutinin HA2 chain | polymer | 182 | 20894.0 | 6 | UniProt (Q9Q0U6) Pfam (PF00509) | Influenza A virus | |
| 3 | K, L, M, N, O... (L, E, J, X, Q...) | H5M9 antibody, light chain (kappa) | polymer | 218 | 24049.5 | 6 | Mus musculus (mouse) | ||
| 4 | S, T, U, V, W... (H, F, K, T, R...) | H5M9 antibody, heavy chain (IgG1) | polymer | 222 | 23935.8 | 6 | Mus musculus (mouse) | ||
| 5 | DA, FA, Y (d, f, Y) | alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 3 | In PDB GlyTouCan (G62182OO) | |||
| 6 | Z (Z) | alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1397.2 | 1 | In PDB GlyTouCan (G48018RF) | |||
| 7 | AA, CA (a, c) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | In PDB GlyTouCan (G42666HT) | |||
| 8 | BA (b) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G15407YE) | |||
| 9 | EA (e) | alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 1 | In PDB GlyTouCan (G81315DD) | |||
| 10 | GA, HA, IA, JA, KA... (A, C, M, O, P...) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 6 | Chemie (NAG) |
Sequence modifications
A, C, G, M, O, S: 11 - 333 (UniProt: Q9Q0U6)
B, D, N, P, I, U: 1 - 175 (UniProt: Q9Q0U6)
| PDB | External Database | Details |
|---|---|---|
| Ala 7 | - | expression tag |
| Asp 8 | - | expression tag |
| Pro 9 | - | expression tag |
| Gly 10 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ser 176 | - | expression tag |
| Gly 177 | - | expression tag |
| Arg 178 | - | expression tag |
| Leu 179 | - | expression tag |
| Val 180 | - | expression tag |
| Pro 181 | - | expression tag |
| Arg 182 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 24 |
| Total formula weight | 640152.0 | |
| Branched | Number of molecules | 8 |
| Total formula weight | 5340.9 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1327.2 | |
| All* | Total formula weight | 646820.2 |
