4MHH
Crystal structure of Fab H5M9 in complex with influenza virus hemagglutinin from A/Viet Nam/1203/2004 (H5N1)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E | Hemagglutinin HA1 chain | polymer | 334 | 37948.0 | 3 | UniProt (Q6DQ33) Pfam (PF00509) UniProt (by SIFTS) (Q9Q0U6) In PDB | Influenza A virus | |
| 2 | L, I, K | H5M9 antibody, light chain (kappa) | polymer | 218 | 24049.5 | 3 | Mus musculus (mouse) | ||
| 3 | B, D, F | Hemagglutinin HA2 chain | polymer | 181 | 20881.1 | 3 | UniProt (Q6DQ33) Pfam (PF00509) UniProt (by SIFTS) (Q6J8F6) In PDB | Influenza A virus | |
| 4 | H, G, J | H5M9 antibody, heavy chain (IgG1) | polymer | 222 | 23935.8 | 3 | Mus musculus (mouse) | ||
| 5 | M, S, X | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 3 | In PDB GlyTouCan (G21381MC) | |||
| 6 | a, N, O, P, R... | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 10 | In PDB GlyTouCan (G42666HT) | |||
| 7 | b, Q, Z | alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 3 | In PDB GlyTouCan (G62182OO) | |||
| 8 | c | alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 1 | In PDB GlyTouCan (G48068RF) | |||
| 9 | L, I, K, F | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 4 | Chemie (NAG) |
Sequence modifications
A, C, E: 11 - 333 (UniProt: Q6DQ33)
B, D, F: 1 - 174 (UniProt: Q6DQ33)
| PDB | External Database | Details |
|---|---|---|
| Ala 7 | - | expression tag |
| Asp 8 | - | expression tag |
| Pro 9 | - | expression tag |
| Gly 10 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ser 175 | - | expression tag |
| Gly 176 | - | expression tag |
| Arg 177 | - | expression tag |
| Leu 178 | - | expression tag |
| Val 179 | - | expression tag |
| Pro 180 | - | expression tag |
| Arg 181 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 320443.2 | |
| Branched | Number of molecules | 17 |
| Total formula weight | 9484.8 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 884.8 | |
| All* | Total formula weight | 330812.8 |
