4MG5
Crystal structure of hERa-LBD (Y537S) in complex with chlordecone
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Estrogen receptor | polymer | 255 | 29070.2 | 2 | UniProt (P03372) Pfam (PF00104) | Homo sapiens (human) | ER,ER-alpha,Estradiol receptor,Nuclear receptor subfamily 3 group A member 1 |
| 2 | C, D (C, D) | Nuclear receptor coactivator 1 | polymer | 13 | 1591.9 | 2 | UniProt (Q15788) | Homo sapiens | NCoA-1,Class E basic helix-loop-helix protein 74,bHLHe74,Protein Hin-2,RIP160,Renal carcinoma antigen NY-REN-52,Steroid receptor coactivator 1,SRC-1 |
| 3 | E, G, H (A, B) | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 4 | F, I (A, B) | chlordecone | non-polymer | 508.7 | 2 | Chemie (A1AQV) | |||
| 5 | J, K, L (A, B, D) | water | water | 18.0 | 160 | Chemie (HOH) |
Sequence modifications
A, B: 302 - 552 (UniProt: P03372)
| PDB | External Database | Details |
|---|---|---|
| Gly 298 | - | expression tag |
| Ser 299 | - | expression tag |
| His 300 | - | expression tag |
| Met 301 | - | expression tag |
| Ser 537 | Tyr 537 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 61324.2 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1293.6 | |
| All* | Total formula weight | 62617.8 |
