4MG2
ALKBH2 F102A cross-linked to undamaged dsDNA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Alpha-ketoglutarate-dependent dioxygenase alkB homolog 2 | polymer | 205 | 23322.7 | 1 | UniProt (Q6NS38) Pfam (PF13532) | Homo sapiens (human) | Alkylated DNA repair protein alkB homolog 2, DNA oxidative demethylase ALKBH2, Oxy DC1 |
| 2 | B (B) | DNA-1 | polymer | 15 | 4618.0 | 1 | |||
| 3 | C (C) | DNA-2 | polymer | 15 | 4572.0 | 1 | |||
| 4 | D (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 5 | E, F (A, B) | water | water | 18.0 | 30 | Chemie (HOH) |
Sequence modifications
A: 56 - 258 (UniProt: Q6NS38)
| PDB | External Database | Details |
|---|---|---|
| Met 55 | - | initiating methionine |
| Ser 67 | Cys 67 | conflict |
| Ala 102 | Phe 102 | engineered mutation |
| Ser 165 | Cys 165 | conflict |
| Cys 169 | Gly 169 | conflict |
| Ser 192 | Cys 192 | conflict |
| Met 259 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 32512.8 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 24.3 | |
| All* | Total formula weight | 32537.1 |
