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4MFF

Structure of human DNA polymerase beta complexed with O6MG in the template base paired with incoming non-hydrolyzable TTP

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
DNA polymerase betapolymer32537081.31UniProt (P06746)
Pfam (PF14716)
Pfam (PF10391)
Pfam (PF14792)
Pfam (PF14791)
Homo sapiens (human)
2B
(T)
templatepolymer164858.21
3C
(P)
up primerpolymer103085.01
4D
(D)
dn primerpolymer51536.01
5E, F
(A)
MAGNESIUM IONnon-polymer24.32Chemie (MG)
6G, I
(A, D)
SODIUM IONnon-polymer23.02Chemie (NA)
7H
(A)
5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]thymidinenon-polymer481.21Chemie (1FZ)
8J, K, L, M
(A, T, P, D)
waterwater18.051Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight46560.5
Non-Polymers*Number of molecules5
Total formula weight575.8
All*Total formula weight47136.3
*Water molecules are not included.

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PDB entries from 2025-06-11

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