4MC2
HIV protease in complex with SA525P
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Protease | polymer | 99 | 10804.8 | 2 | UniProt (P0C6F2) Pfam (PF00077) In PDB | Human immunodeficiency virus 1 (HIV-1) | PR, Retropepsin |
| 2 | A, B | (3S)-tetrahydrofuran-3-yl {(2S,3R)-4-[(4R)-4-tert-butyl-7-fluoro-1,1-dioxido-4,5-dihydro-1,2-benzothiazepin-2(3H)-yl]-3-hydroxy-1-phenylbutan-2-yl}carbamate | non-polymer | 548.7 | 2 | Chemie (525) | |||
| 3 | A, B | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 4 | water | water | 18.0 | 178 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 99 (UniProt: P0C6F2)
| PDB | External Database | Details |
|---|---|---|
| Lys 7 | Gln 495 | engineered mutation |
| Ile 33 | Leu 521 | engineered mutation |
| Ile 63 | Leu 551 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 21609.6 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1168.2 | |
| All* | Total formula weight | 22777.9 |
