4MBK
Crystal structure of K234R inhibitor-resistant variant of SHV beta-lactamase in complex with SA2-13
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Beta-lactamase SHV-1 | polymer | 265 | 28935.0 | 1 | UniProt (P0AD64) Pfam (PF00144) Pfam (PF13354) | Klebsiella pneumoniae | PIT-2 |
| 2 | B, C (A) | CYCLOHEXYL-HEXYL-BETA-D-MALTOSIDE | non-polymer | 508.6 | 2 | Chemie (MA4) | |||
| 3 | D (A) | (3R)-4-[(4-CARBOXYBUTANOYL)OXY]-N-[(1E)-3-OXOPROP-1-EN-1-YL]-3-SULFINO-D-VALINE | non-polymer | 365.4 | 1 | Chemie (SA2) | |||
| 4 | E (A) | water | water | 18.0 | 161 | Chemie (HOH) |
Sequence modifications
A: 26 - 292 (UniProt: P0AD64)
| PDB | External Database | Details |
|---|---|---|
| Arg 234 | Lys 230 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 28935.0 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 1382.6 | |
| All* | Total formula weight | 30317.6 |
