4M9J
DNA Polymerase Beta E295K Soaked with dUMPNPP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | DNA polymerase beta | polymer | 335 | 38241.7 | 1 | UniProt (P06746) Pfam (PF14716) Pfam (PF10391) Pfam (PF14792) Pfam (PF14791) | Homo sapiens (human) | |
| 2 | B (T) | DNA Template Strand | polymer | 16 | 4853.2 | 1 | |||
| 3 | C (P) | DNA Primer Strand | polymer | 10 | 3061.0 | 1 | |||
| 4 | D (D) | DNA Downstream Strand | polymer | 5 | 1536.0 | 1 | |||
| 5 | E, F (A) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 6 | G, H (A) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 7 | I (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 8 | J (A) | 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE | non-polymer | 467.2 | 1 | Chemie (DUP) | |||
| 9 | K, L, M, N (A, T, P, D) | water | water | 18.0 | 339 | Chemie (HOH) |
Sequence modifications
A: 1 - 335 (UniProt: P06746)
| PDB | External Database | Details |
|---|---|---|
| Lys 295 | Glu 295 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 47691.9 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 608.3 | |
| All* | Total formula weight | 48300.3 |
