4M66

Crystal structure of the mouse RIP3 kinase domain

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Receptor-interacting serine/threonine-protein kinase 3	polymer	325	36213.3	2	UniProt (Q9QZL0) Pfam (PF00069)	Mus musculus (mouse)	RIP-like protein kinase 3, Receptor-interacting protein 3, RIP-3, mRIP3
2	C, D (A, B)	water	water		18.0	106	Chemie (HOH)

Sequence modifications

A, B: 1 - 313 (UniProt: Q9QZL0)

PDB	External Database	Details
Ala 111	Cys 111	engineered mutation
Leu 314	-	expression tag
Glu 315	-	expression tag
His 316	-	expression tag
His 317	-	expression tag
His 318	-	expression tag
His 319	-	expression tag
His 320	-	expression tag
His 321	-	expression tag
His 322	-	expression tag
His 323	-	expression tag
His 324	-	expression tag
His 325	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	72426.7
All*	Total formula weight	72426.7

*Water molecules are not included.