4M4U
Structural evaluation D84A mutant of the aspergillus fumigatus kdnase (sialidase)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Extracellular sialidase/neuraminidase, putative | polymer | 422 | 46232.6 | 2 | UniProt (Q4WQS0) Pfam (PF13088) In PDB | Aspergillus fumigatus | |
2 | A | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
3 | A, B | GLYCEROL | non-polymer | 92.1 | 7 | Chemie (GOL) | |||
4 | A, B | PHOSPHATE ION | non-polymer | 95.0 | 2 | Chemie (PO4) | |||
5 | A | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
6 | B | NITRATE ION | non-polymer | 62.0 | 2 | Chemie (NO3) | |||
7 | B | NITRITE ION | non-polymer | 46.0 | 1 | Chemie (NO2) | |||
8 | water | water | 18.0 | 1162 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 406 (UniProt: Q4WQS0)
PDB | External Database | Details |
---|---|---|
His -15 | - | expression tag |
His -14 | - | expression tag |
His -13 | - | expression tag |
His -12 | - | expression tag |
His -11 | - | expression tag |
His -10 | - | expression tag |
Ser -9 | - | expression tag |
Ser -8 | - | expression tag |
Gly -7 | - | expression tag |
Leu -6 | - | expression tag |
Val -5 | - | expression tag |
Pro -4 | - | expression tag |
Arg -3 | - | expression tag |
Gly -2 | - | expression tag |
Ser -1 | - | expression tag |
His 0 | - | expression tag |
Ala 84 | Asp 84 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 92465.2 | |
Non-Polymers* | Number of molecules | 14 |
Total formula weight | 1063.1 | |
All* | Total formula weight | 93528.2 |