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4M47

structure of human DNA polymerase complexed with 8-BrG in the template base paired with incoming non-hydrolyzable GTP

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
DNA polymerase betapolymer32436968.21UniProt (P06746)
Pfam (PF14716)
Pfam (PF10391)
Pfam (PF14792)
Pfam (PF14791)
Homo sapiens (human)
2B
(T)
a synthetic templatepolymer164923.01
3C
(P)
a synthetic upstream primerpolymer103085.01
4D
(D)
a synthetic downstream primerpolymer51536.01
5E
(A)
2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosinenon-polymer506.21Chemie (XG4)
6F
(A)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
7G, H, I
(A)
SODIUM IONnon-polymer23.03Chemie (NA)
8J, K, L, M
(A, T, P, D)
waterwater18.058Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight46512.3
Non-Polymers*Number of molecules5
Total formula weight599.5
All*Total formula weight47111.7
*Water molecules are not included.

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PDB entries from 2025-06-11

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