4M1G
Structure of murine IgG2a A27D7-Fab in complex with vaccinia antigen A33R at the resolution of 1.6 Angstroms
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (L) | Murine IgG2a A27D7 Light chain Fab domain | polymer | 215 | 23410.9 | 1 | Mus musculus | ||
| 2 | B (H) | Murine IgG2a A27D7 Heavy chain Fab domain | polymer | 220 | 23358.2 | 1 | Mus musculus | ||
| 3 | C, D (A, B) | A33R | polymer | 97 | 11049.0 | 2 | UniProt (Q71TT1) Pfam (PF05966) | Vaccinia virus | EEV glycoprotein, EEV membrane glycoprotein, EEV membrane phosphoglycoprotein, VACV-DUKE-164, VACV152 |
| 4 | E, F (L) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 5 | G, H, I, J (L, H, A, B) | water | water | 18.0 | 483 | Chemie (HOH) |
Sequence modifications
A, B: 89 - 185 (UniProt: Q71TT1)
| PDB | External Database | Details |
|---|---|---|
| Met 89 | Ser 89 | engineered mutation |
| Met 118 | Leu 118 | engineered mutation |
| Ala 123 | Lys 123 | engineered mutation |
| Met 140 | Leu 140 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 68867.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 192.1 | |
| All* | Total formula weight | 69059.2 |
