4M18
Crystal Structure of Surfactant Protein-D D325A/R343V mutant in complex with trimannose (Man-a1,2Man-a1,2Man)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... | Pulmonary surfactant-associated protein D | polymer | 147 | 15881.7 | 12 | UniProt (P35247) Pfam (PF09006) Pfam (PF00059) In PDB | Homo sapiens (human) | PSP-D, SP-D, Collectin-7, Lung surfactant protein D |
| 2 | M, N, P, Q, R... | alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose | branched | 504.4 | 10 | In PDB GlyTouCan (G25559RS) | |||
| 3 | O, V | alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose | branched | 342.3 | 2 | In PDB BIRD (PRD_900111) GlyTouCan (G53402KW) | 2alpha-alpha-mannobiose | ||
| 4 | A, I, J, B, K... | CALCIUM ION | non-polymer | 40.1 | 38 | Chemie (CA) | |||
| 5 | water | water | 18.0 | 14 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G, H, I, J, K, L: 209 - 355 (UniProt: P35247)
| PDB | External Database | Details |
|---|---|---|
| Ala 325 | Asp 345 | engineered mutation |
| Val 343 | Arg 363 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 190580.2 | |
| Branched | Number of molecules | 12 |
| Total formula weight | 5729.0 | |
| Non-Polymers* | Number of molecules | 38 |
| Total formula weight | 1523.0 | |
| All* | Total formula weight | 197832.1 |
