4M04
Human DNA Polymerase Mu ternary complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | DNA-directed DNA/RNA polymerase mu | polymer | 356 | 40054.4 | 1 | UniProt (Q9NP87) Pfam (PF14716) Pfam (PF10391) Pfam (PF14792) Pfam (PF14791) | Homo sapiens (human) | Pol Mu, Terminal transferase |
| 2 | B (T) | template strand | polymer | 9 | 2740.8 | 1 | |||
| 3 | C (P) | upstream primer strand | polymer | 4 | 1190.8 | 1 | |||
| 4 | D (D) | downstream primer strand | polymer | 4 | 1191.8 | 1 | |||
| 5 | E (A) | 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE | non-polymer | 467.2 | 1 | Chemie (DUP) | |||
| 6 | F, G (A) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 7 | H, I, L (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
| 8 | J (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 9 | K (A) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 10 | M (A) | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID | non-polymer | 238.3 | 1 | Chemie (EPE) | |||
| 11 | N, O, P, Q (A, T, P, D) | water | water | 18.0 | 381 | Chemie (HOH) |
Sequence modifications
A: 132 - 494 (UniProt: Q9NP87)
| PDB | External Database | Details |
|---|---|---|
| Gly 127 | - | expression tag |
| Ser 128 | - | expression tag |
| Ala 129 | - | expression tag |
| Ala 130 | - | expression tag |
| Ala 131 | - | expression tag |
| - | Pro 398 | deletion |
| - | Gly 399 | deletion |
| - | Ala 400 | deletion |
| - | Ala 401 | deletion |
| - | Val 402 | deletion |
| - | Gly 403 | deletion |
| - | Gly 404 | deletion |
| - | Ser 405 | deletion |
| - | Thr 406 | deletion |
| - | Arg 407 | deletion |
| - | Pro 408 | deletion |
| - | Cys 409 | deletion |
| - | Pro 410 | deletion |
| Gly 410 | - | insertion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 45177.9 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 998.7 | |
| All* | Total formula weight | 46176.6 |
