4LZ4
X-ray structure of the complex between human thrombin and the TBA deletion mutant lacking thymine 3 nucleobase
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, C | Thrombin light chain | polymer | 36 | 4096.5 | 2 | UniProt (P00734) Pfam (PF09396) In PDB | Homo sapiens (human) | Coagulation factor II, Activation peptide fragment 1, Activation peptide fragment 2, Thrombin light chain |
2 | B, D | Thrombin heavy chain | polymer | 259 | 29780.2 | 2 | UniProt (P00734) Pfam (PF00089) In PDB | Homo sapiens (human) | Coagulation factor II, Activation peptide fragment 1, Activation peptide fragment 2, Thrombin heavy chain |
3 | E, F | Thrombin Binding Aptamer (TBA) | polymer | 15 | 4619.0 | 2 | |||
4 | B, D | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
5 | B, D | D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide | non-polymer | 454.0 | 2 | BIRD (PRD_000020) Chemie (0G6) | |||
6 | B, D | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
7 | E, F | POTASSIUM ION | non-polymer | 39.1 | 2 | Chemie (K) | |||
8 | water | water | 18.0 | 219 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 76991.4 | |
Non-Polymers* | Number of molecules | 8 |
Total formula weight | 1474.6 | |
All* | Total formula weight | 78466.0 |