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4LZ4

X-ray structure of the complex between human thrombin and the TBA deletion mutant lacking thymine 3 nucleobase

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, CThrombin light chainpolymer364096.52UniProt (P00734)
Pfam (PF09396)
In PDB
Homo sapiens (human)Coagulation factor II, Activation peptide fragment 1, Activation peptide fragment 2, Thrombin light chain
2B, DThrombin heavy chainpolymer25929780.22UniProt (P00734)
Pfam (PF00089)
In PDB
Homo sapiens (human)Coagulation factor II, Activation peptide fragment 1, Activation peptide fragment 2, Thrombin heavy chain
3E, FThrombin Binding Aptamer (TBA)polymer154619.02
4B, D2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.22Chemie (NAG)
5B, DD-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamidenon-polymer454.02BIRD (PRD_000020)
Chemie (0G6)
6B, DSODIUM IONnon-polymer23.02Chemie (NA)
7E, FPOTASSIUM IONnon-polymer39.12Chemie (K)
8waterwater18.0219Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains6
Total formula weight76991.4
Non-Polymers*Number of molecules8
Total formula weight1474.6
All*Total formula weight78466.0
*Water molecules are not included.

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PDB entries from 2024-09-18

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