4LXS
Structure of the Toll - Spatzle complex, a molecular hub in Drosophila development and innate immunity (glycosylated form)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Protein toll | polymer | 783 | 89632.4 | 1 | UniProt (P08953) Pfam (PF13855) Pfam (PF00560) Pfam (PF01463) Pfam (PF01462) | Drosophila melanogaster (Fruit fly) | |
| 2 | B, C (J, K) | Protein spaetzle C-106 | polymer | 114 | 13006.6 | 2 | UniProt (P48607) Pfam (PF16077) | Drosophila melanogaster (Fruit fly) | |
| 3 | D (B) | alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 1 | In PDB GlyTouCan (G52322TF) | |||
| 4 | E, G, H, I, J (C, E, F, G, H) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 5 | In PDB GlyTouCan (G42666HT) | |||
| 5 | F (D) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G15407YE) | |||
| 6 | K, L, M, N, O (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 5 | Chemie (NAG) | |||
| 7 | P (A) | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID | non-polymer | 238.3 | 1 | Chemie (EPE) |
Sequence modifications
A: 28 - 802 (UniProt: P08953)
J, K: 1 - 106 (UniProt: P48607)
| PDB | External Database | Details |
|---|---|---|
| Thr 803 | - | expression tag |
| Gly 804 | - | expression tag |
| His 805 | - | expression tag |
| His 806 | - | expression tag |
| His 807 | - | expression tag |
| His 808 | - | expression tag |
| His 809 | - | expression tag |
| His 810 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Leu 107 | - | expression tag |
| Glu 108 | - | expression tag |
| His 109 | - | expression tag |
| His 110 | - | expression tag |
| His 111 | - | expression tag |
| His 112 | - | expression tag |
| His 113 | - | expression tag |
| His 114 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 115645.6 | |
| Branched | Number of molecules | 7 |
| Total formula weight | 3619.4 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1344.3 | |
| All* | Total formula weight | 120609.3 |
