4LX0

Crystal structure of Myo5b globular tail domain in complex with active Rab11a

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (A, C)	Ras-related protein Rab-11A	polymer	177	19972.5	2	UniProt (P62491) Pfam (PF00071)	Homo sapiens (human)	Rab-11, YL8
2	B, D (B, D)	Unconventional myosin-Vb	polymer	427	49240.4	2	UniProt (Q9ULV0) Pfam (PF01843)	Homo sapiens (human)
3	E, I (A, C)	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
4	F, J (A, C)	BERYLLIUM TRIFLUORIDE ION	non-polymer		66.0	2	Chemie (BEF)
5	G, K (A, C)	GUANOSINE-5'-DIPHOSPHATE	non-polymer		443.2	2	Chemie (GDP)
6	H (A)	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
7	L, M, N, O (A, B, C, D)	water	water		18.0	651	Chemie (HOH)

Sequence modifications

B, D: 1456 - 1848 (UniProt: Q9ULV0)

PDB	External Database	Details
Met 1423	-	expression tag
Arg 1424	-	expression tag
Ser 1425	-	expression tag
Glu 1426	-	expression tag
Thr 1427	-	expression tag
Met 1428	-	expression tag
Ser 1429	-	expression tag
Tyr 1430	-	expression tag
Tyr 1431	-	expression tag
His 1432	-	expression tag
His 1433	-	expression tag
His 1434	-	expression tag
His 1435	-	expression tag
His 1436	-	expression tag
His 1437	-	expression tag
Asp 1438	-	expression tag
Tyr 1439	-	expression tag
Asp 1440	-	expression tag
Ile 1441	-	expression tag
Pro 1442	-	expression tag
Thr 1443	-	expression tag
Thr 1444	-	expression tag
Glu 1445	-	expression tag
Asn 1446	-	expression tag
Leu 1447	-	expression tag
Tyr 1448	-	expression tag
Phe 1449	-	expression tag
Gln 1450	-	expression tag
Gly 1451	-	expression tag
Ala 1452	-	expression tag
Met 1452	-	expression tag
Gly 1452	-	expression tag
Ser 1452	-	expression tag
Met 1455	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	138425.8
Non-Polymers*	Number of molecules	7
	Total formula weight	1159.1
All*	Total formula weight	139584.9

*Water molecules are not included.