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4LWE

Crystal Structure of the human Hsp90-alpha N-domain bound to the hsp90 inhibitor FJ2

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Heat shock protein HSP 90-alphapolymer20823263.41UniProt (P07900)
Pfam (PF13589)
Homo sapiens (human)Heat shock 86 kDa, HSP 86, HSP86, Renal carcinoma antigen NY-REN-38
2B
(A)
N-[3-(5-chloro-2,4-dihydroxyphenyl)-4-(4-methoxyphenyl)-1,2-oxazol-5-yl]acetamidenon-polymer374.81Chemie (FJ2)
3C
(A)
waterwater18.0161Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight23263.4
Non-Polymers*Number of molecules1
Total formula weight374.8
All*Total formula weight23638.2
*Water molecules are not included.

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PDB entries from 2025-08-27

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