4LTA
The crystal structure of the P132R, Y133G mutant of Pyrococcus furiosus phosphoglucose isomerase in complex with manganese and 5-phospho-D-arabinonate.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Glucose-6-phosphate isomerase | polymer | 189 | 21459.4 | 2 | UniProt (P83194) Pfam (PF06560) | Pyrococcus furiosus | GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI |
| 2 | C, G (A, B) | MANGANESE (II) ION | non-polymer | 54.9 | 2 | Chemie (MN) | |||
| 3 | D, H (A, B) | 5-PHOSPHOARABINONIC ACID | non-polymer | 246.1 | 2 | Chemie (PA5) | |||
| 4 | E, F, I, J (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 4 | Chemie (EDO) | |||
| 5 | K, L (A, B) | water | water | 18.0 | 140 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 189 (UniProt: P83194)
| PDB | External Database | Details |
|---|---|---|
| Arg 132 | Pro 132 | engineered mutation |
| Gly 133 | Tyr 133 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 42918.8 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 850.4 | |
| All* | Total formula weight | 43769.1 |
