4LSG

Structure of Mouse P-Glycoprotein

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Multidrug resistance protein 1A	polymer	1284	141845.8	2	UniProt (P21447) Pfam (PF00664) Pfam (PF00005) In PDB	Mus musculus (mouse)	ATP-binding cassette sub-family B member 1A, MDR1A, Multidrug resistance protein 3, P-glycoprotein 3
2	A, B	MERCURY (II) ION	non-polymer		200.6	12	Chemie (HG)

Sequence modifications

A, B: 1 - 1276 (UniProt: P21447)

PDB	External Database	Details
Ala 952	Cys 952	engineered mutation
Leu 1277	-	expression tag
Glu 1278	-	expression tag
His 1279	-	expression tag
His 1280	-	expression tag
His 1281	-	expression tag
His 1282	-	expression tag
His 1283	-	expression tag
His 1284	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	283691.6
Non-Polymers*	Number of molecules	12
	Total formula weight	2407.1
All*	Total formula weight	286098.7

*Water molecules are not included.