4LRG
Structure of BRD4 bromodomain 1 with a dimethyl thiophene isoxazole azepine carboxamide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Bromodomain-containing protein 4 | polymer | 128 | 15126.3 | 1 | UniProt (O60885) Pfam (PF00439) | Homo sapiens (human) | Protein HUNK1 |
| 2 | B (A) | 2-[(6S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-[1,2]oxazolo[5,4-c]thieno[2,3-e]azepin-6-yl]acetamide | non-polymer | 399.9 | 1 | Chemie (1XB) | |||
| 3 | C (A) | water | water | 18.0 | 108 | Chemie (HOH) |
Sequence modifications
A: 42 - 168 (UniProt: O60885)
| PDB | External Database | Details |
|---|---|---|
| Gly 41 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 15126.3 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 399.9 | |
| All* | Total formula weight | 15526.2 |
