4LPF

Crystal structure of Mycobacterium tuberculosis imidazole glycerol phosphate dehydratase in complex with an inhibitor

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Imidazoleglycerol-phosphate dehydratase	polymer	216	23633.5	1	UniProt (I6XBW5) In PDB	Mycobacterium tuberculosis H37Rv	IGPD
2	A	3-AMINO-1,2,4-TRIAZOLE	non-polymer		84.1	1	Chemie (3TR)
3	A	MANGANESE (II) ION	non-polymer		54.9	3	Chemie (MN)
4		water	water		18.0	71	Chemie (HOH)

Sequence modifications

A: 2 - 210 (UniProt: I6XBW5)

PDB	External Database	Details
Met -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag
His 1	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	23633.5
Non-Polymers*	Number of molecules	4
	Total formula weight	248.9
All*	Total formula weight	23882.4

*Water molecules are not included.