4LP6

Crystal Structure of Human Carbonic Anhydrase II in complex with a quinoline oligoamide foldamer

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Carbonic anhydrase 2	polymer	260	29289.1	2	UniProt (P00918) Pfam (PF00194) In PDB	Homo sapiens (human)	Carbonate dehydratase II, Carbonic anhydrase C, CAC, Carbonic anhydrase II, CA-II
2	A, B	8-({[4-(3-aminopropoxy)-8-({[4-hydroxy-8-({[4-(2-methylpropoxy)-8-({[4-(3-{[(4-sulfamoylbenzoyl)amino]methyl}phenoxy)butyl]carbamoyl}amino)quinolin-2-yl]carbonyl}amino)quinolin-2-yl]carbonyl}amino)quinolin-2-yl]carbonyl}amino)-4-(carboxymethoxy)quinoline-2-carboxylic acid	non-polymer		1337.4	2	Chemie (Q4I)
3	A, B	ZINC ION	non-polymer		65.4	13	Chemie (ZN)
4		water	water		18.0	148	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	58578.1
Non-Polymers*	Number of molecules	15
	Total formula weight	3525.1
All*	Total formula weight	62103.2

*Water molecules are not included.