4LP6
Crystal Structure of Human Carbonic Anhydrase II in complex with a quinoline oligoamide foldamer
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Carbonic anhydrase 2 | polymer | 260 | 29289.1 | 2 | UniProt (P00918) Pfam (PF00194) In PDB | Homo sapiens (human) | Carbonate dehydratase II, Carbonic anhydrase C, CAC, Carbonic anhydrase II, CA-II |
2 | A, B | 8-({[4-(3-aminopropoxy)-8-({[4-hydroxy-8-({[4-(2-methylpropoxy)-8-({[4-(3-{[(4-sulfamoylbenzoyl)amino]methyl}phenoxy)butyl]carbamoyl}amino)quinolin-2-yl]carbonyl}amino)quinolin-2-yl]carbonyl}amino)quinolin-2-yl]carbonyl}amino)-4-(carboxymethoxy)quinoline-2-carboxylic acid | non-polymer | 1337.4 | 2 | Chemie (Q4I) | |||
3 | A, B | ZINC ION | non-polymer | 65.4 | 13 | Chemie (ZN) | |||
4 | water | water | 18.0 | 148 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 58578.1 | |
Non-Polymers* | Number of molecules | 15 |
Total formula weight | 3525.1 | |
All* | Total formula weight | 62103.2 |