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4LOF

Human p53 Core Domain Mutant V157F/N235K/N239Y

Replaces:  2QVQ
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Cellular tumor antigen p53polymer21924699.11UniProt (P04637)
Pfam (PF00870)
Homo sapiens (human)Antigen NY-CO-13, Phosphoprotein p53, Tumor suppressor p53
2B
(A)
ZINC IONnon-polymer65.41Chemie (ZN)
3C
(A)
waterwater18.0134Chemie (HOH)
Sequence modifications
A: 94 - 312 (UniProt: P04637)
PDBExternal DatabaseDetails
Phe 157Val 157engineered mutation
Lys 235Asn 235engineered mutation
Tyr 239Asn 239engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight24699.1
Non-Polymers*Number of molecules1
Total formula weight65.4
All*Total formula weight24764.5
*Water molecules are not included.

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PDB entries from 2025-06-11

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