4LND
Crystal structure of human apurinic/apyrimidinic endonuclease 1 with essential Mg2+ cofactor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | DNA-(apurinic or apyrimidinic site) lyase | polymer | 286 | 32100.5 | 3 | UniProt (P27695) Pfam (PF03372) | Homo sapiens (human) | APEX nuclease, APEN, Apurinic-apyrimidinic endonuclease 1, AP endonuclease 1, APE-1, REF-1, Redox factor-1, DNA-(apurinic or apyrimidinic site) lyase, mitochondrial |
| 2 | D, E, F (A, B, C) | MAGNESIUM ION | non-polymer | 24.3 | 3 | Chemie (MG) | |||
| 3 | G, H, I (A, B, C) | water | water | 18.0 | 120 | Chemie (HOH) |
Sequence modifications
A, B, C: 39 - 318 (UniProt: P27695)
| PDB | External Database | Details |
|---|---|---|
| Gly 33 | - | expression tag |
| Ser 34 | - | expression tag |
| His 35 | - | expression tag |
| Met 36 | - | expression tag |
| Ala 37 | - | expression tag |
| Ser 38 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 96301.5 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 72.9 | |
| All* | Total formula weight | 96374.4 |
