4LLJ
Crystal structure of PDE10A2 with fragment ZT214
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | polymer | 345 | 39479.2 | 2 | UniProt (Q9Y233) In PDB | Homo sapiens (human) | |
| 2 | A | 2H-isoindole-1,3-diamine | non-polymer | 147.2 | 1 | Chemie (1XN) | |||
| 3 | A, B | NICKEL (II) ION | non-polymer | 58.7 | 4 | Chemie (NI) | |||
| 4 | water | water | 18.0 | 358 | Chemie (HOH) |
Sequence modifications
A, B: 449 - 789 (UniProt: Q9Y233)
| PDB | External Database | Details |
|---|---|---|
| Gly 445 | - | expression tag |
| Ala 446 | - | expression tag |
| Gly 447 | - | expression tag |
| Thr 448 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 78958.5 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 381.9 | |
| All* | Total formula weight | 79340.4 |
