4LEY

Structure of mouse cGAS bound to 18 bp DNA

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Cyclic GMP-AMP synthase	polymer	366	42984.7	4	UniProt (Q8C6L5) Pfam (PF03281) Pfam (PF20266)	Mus musculus (mouse)	cGAMP synthase, cGAS, m-cGAS, Mab-21 domain-containing protein 1
2	E, F, G, H, I... (E, F, G, H, I...)	18 bp dsDNA	polymer	18	5514.6	8
3	M, N, O, P (A, B, C, D)	ZINC ION	non-polymer		65.4	4	Chemie (ZN)
4	AA, BA, Q, R, S... (K, L, A, B, C...)	water	water		18.0	631	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	216055.5
Non-Polymers*	Number of molecules	4
	Total formula weight	261.6
All*	Total formula weight	216317.1

*Water molecules are not included.