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4LEQ

tRNA guanine transglycosylase (TGT) in complex with Furanoside-Based lin-Benzoguanine 1

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Queuine tRNA-ribosyltransferasepolymer38843069.81UniProt (P28720)
Pfam (PF01702)
Zymomonas Mobilis subsp. mobilisGuanine insertion enzyme, tRNA-guanine transglycosylase
2B
(A)
methyl 6-[6-amino-2-(methylamino)-8-oxo-7,8-dihydro-1H-imidazo[4,5-g]quinazolin-4-yl]-5,6-dideoxy-beta-D-ribo-hexofuranosidenon-polymer390.41Chemie (1WK)
3C, D
(A)
GLYCEROLnon-polymer92.12Chemie (GOL)
4E
(A)
ZINC IONnon-polymer65.41Chemie (ZN)
5F
(A)
CHLORIDE IONnon-polymer35.51Chemie (CL)
6G
(A)
waterwater18.0428Chemie (HOH)
Sequence modifications
A: 1 - 386 (UniProt: P28720)
PDBExternal DatabaseDetails
Gly -1-expression tag
Ser 0-expression tag
Lys 312Thr 312conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight43069.8
Non-Polymers*Number of molecules5
Total formula weight675.4
All*Total formula weight43745.3
*Water molecules are not included.

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PDB entries from 2025-12-10

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