4LBK
Crystal structure of Human galectin-3 CRD K176L mutant in complex with LNnT
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Galectin-3 | polymer | 138 | 15719.1 | 1 | UniProt (P17931) Pfam (PF00337) | Homo sapiens (human) | Gal-3, 35 kDa lectin, Carbohydrate-binding protein 35, CBP 35, Galactose-specific lectin 3, Galactoside-binding protein, GALBP, IgE-binding protein, L-31, Laminin-binding protein, Lectin L-29, Mac-2 antigen |
| 2 | B (B) | beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-beta-D-galactopyranose-(1-4)-beta-D-glucopyranose | branched | 707.6 | 1 | In PDB GlyTouCan (G58896AZ) | |||
| 3 | C (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 4 | D (A) | water | water | 18.0 | 182 | Chemie (HOH) |
Sequence modifications
A: 114 - 250 (UniProt: P17931)
| PDB | External Database | Details |
|---|---|---|
| Met 113 | - | expression tag |
| Leu 176 | Lys 176 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 15719.1 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 707.6 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 35.5 | |
| All* | Total formula weight | 16462.2 |
