4LB7
Crystal structure of human alpha-defensin 1 (HNP1) Y16A/I20A/L25A/F28A mutant.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | D, E, A, B | Neutrophil defensin 1 | polymer | 30 | 3199.8 | 4 | UniProt (P59665) Pfam (PF00323) In PDB | Homo sapiens | Defensin, alpha 1, HNP-1, HP-1, HP1, HP 1-56, Neutrophil defensin 2, HNP-2, HP-2, HP2 |
| 2 | water | water | 18.0 | 8 | Chemie (HOH) |
Sequence modifications
D, E, A, B: 1 - 30 (UniProt: P59665)
| PDB | External Database | Details |
|---|---|---|
| Ala 16 | Tyr 80 | engineered mutation |
| Ala 20 | Ile 84 | engineered mutation |
| Ala 25 | Leu 89 | engineered mutation |
| Ala 28 | Phe 92 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 12799.0 | |
| All* | Total formula weight | 12799.0 |
