4LB1

Crystal structure of human alpha-defensin 1 (HNP1) Y16A/F28A mutant

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (D, E, A, B)	Neutrophil defensin 1	polymer	30	3283.9	4	UniProt (P59665) Pfam (PF00323)	Homo sapiens	Defensin, alpha 1, HNP-1, HP-1, HP1, HP 1-56, Neutrophil defensin 2, HNP-2, HP-2, HP2
2	E, F, G, H (D, E, A, B)	water	water		18.0	8	Chemie (HOH)

Sequence modifications

D, E, A, B: 1 - 30 (UniProt: P59665)

PDB	External Database	Details
Ala 16	Tyr 80	engineered mutation
Ala 28	Phe 92	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	13135.7
All*	Total formula weight	13135.7

*Water molecules are not included.