4L9S
Crystal Structure of H-Ras G12C, GDP-bound
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | GTPase HRas | polymer | 171 | 19324.7 | 1 | UniProt (P01112) Pfam (PF00071) In PDB | Homo sapiens (human) | H-Ras-1, Ha-Ras, Transforming protein p21, c-H-ras, p21ras, GTPase HRas, N-terminally processed |
2 | A | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 1 | Chemie (GDP) | |||
3 | A | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
4 | A | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
5 | A | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
6 | water | water | 18.0 | 167 | Chemie (HOH) |
Sequence modifications
A: 1 - 166 (UniProt: P01112)
PDB | External Database | Details |
---|---|---|
Gly -4 | - | expression tag |
Ala -3 | - | expression tag |
Met -2 | - | expression tag |
Gly -1 | - | expression tag |
Ser 0 | - | expression tag |
Cys 12 | Gly 12 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 19324.7 | |
Non-Polymers* | Number of molecules | 6 |
Total formula weight | 593.6 | |
All* | Total formula weight | 19918.4 |