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4L7U

Human artd3 (parp3) - catalytic domain in complex with inhibitor ME0398

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1APoly [ADP-ribose] polymerase 3polymer35739752.11UniProt (Q9Y6F1)
Pfam (PF02877)
Pfam (PF00644)
In PDB
Homo sapiens (human)PARP-3, hPARP-3, ADP-ribosyltransferase diphtheria toxin-like 3, ARTD3, IRT1, NAD(+) ADP-ribosyltransferase 3, ADPRT-3, Poly[ADP-ribose] synthase 3, pADPRT-3
2Amethyl N-[3-(4-oxo-3,4-dihydroquinazolin-2-yl)propanoyl]-L-phenylalaninatenon-polymer379.41Chemie (1VC)
Sequence modifications
A: 178 - 532 (UniProt: Q9Y6F1)
PDBExternal DatabaseDetails
Ser 176-expression tag
Met 177-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight39752.1
Non-Polymers*Number of molecules1
Total formula weight379.4
All*Total formula weight40131.5
*Water molecules are not included.

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PDB entries from 2024-07-31

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